IRVINE, Calif. — May 5, 2023 — Immunis, Inc., a private biotechnology company developing a novel treatment for age and disease-related immune decline, received the 2023 Global Health and Pharma Biotechnology Award for “Best Immune Deficit Treatment Development.” Global Health and Pharma (GHP) is an online magazine that showcases the latest innovations in biotech. All nominated companies were judged in-house by a select research team, thus ensuring all awards were merit-based.

GHP magazine has a readership of over 110,000, providing exposure for biotech companies like Immunis to share their biomedical mission with the masses. This year, Immunis’ investigational stem cell-derived secretome product (STEM) was the outstanding competitor.

STEM was created to address the age-related decline in immune system health, which manifests in conditions such as Alzheimer’s disease, cancer and sarcopenia. As we age, our immune system function declines and we experience a decrease in the production of beneficial cellular secretions. These secretions, collectively referred to as the secretome, are necessary for modulating immune responses to combat disease.

Conditions like sarcopenia are an important risk factor for disability and mortality. However, mitigating the loss of muscle and improving muscle recovery are unmet medical needs. Remarkably, preclinical researchshows that the STEM secretome enhances muscle size and strength following atrophy. Immunis is amid a Phase 1/2a clinical trial to investigate the safety and efficacy of STEM in patients with muscle atrophy associated with knee osteoarthritis.

“Due to its multi-component mix of molecules associated with cellular function and tissue remodeling, I wouldn’t be surprised if STEM has large, beneficial impacts on other manifestations of age-related diseases,” said Professor Drummond, Scientific Advisory Board Member of Immunis.

Immunis is honored by GHP’s recognition of STEM as this year’s “Best Immune Deficit Treatment Development” and is looking forward to assessing the results of our ongoing clinical trial. Immunis would also like to express gratitude to its incredibly talented and dedicated team that strives to enhance human health.

About Global Health and Pharma

GHP magazine serves as an informational platform for healthcare and pharmaceutical industries. With a circulation of 110,000 globally, GHP aims to support and showcase the latest and most promising innovations across the medical and health industries. For more information please visit: www.ghp-news.com

About Immunis Inc.

Immunis is a private biotechnology company developing a novel immunomodulatory secretome product for the various manifestations of age and disease-related immune decline. The STEM product line leverages Immunis’ leading-edge capabilities in stem cell technologies to deliver a product of all natural, all human immune modulators in their natural relative physiological concentrations. For additional information about Immunis’ IMM01-STEM Phase 1/2a trial please visit: www.immunisbiomedical.com

About STEM-MYO

Immunis’ FDA-awarded Phase 1/2a clinical trial is an open-label dose escalation study to assess the safety and tolerability of IMM01-STEM in elderly participants with muscle atrophy associated with knee osteoarthritis. Up to 18 patients will be enrolled in the trial and randomly assigned to an IMM01-STEM dose cohort. Treatment will be administered in the form of intramuscular injections twice a week for four weeks (8 injections total). Male or female patients are eligible for the study if they satisfy the following criteria: (1) 50 to 75 years of age at the time of signing the informed consent, (2) have a grade 2 or 3 knee osteoarthritis as defined by Kellgren-Lawrence analyses, (3) have quadricep weakness (<7.5N/kg), (4) can ambulate >50 feet unassisted, (5) are negative for human immunodeficiency virus, hepatitis B surface antigen (HBsAg), and hepatitis C at the Screening Visit and (6) have a body mass index (BMI) of <40kg/m². For additional information about Immunis’ trial participant qualifications, please visit:  www.immunisbiomedical.com

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